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2020-21 NCAA Banned Substances

Download: 2020-21 NCAA Banned Substances (pdf)

NCAA Division I Bylaw 12 and NCAA Divisions II and III Bylaw 14 require that schools provide drug education to all student-athletes. The athletics director or the athletics director's designee shall disseminate the list of banned drug classes to all student-athletes and educate them about products that might contain banned drugs. All student-athletes are to be notified that the list may change during the academic year, that updates may be found on the NCAA website ( and informed of the appropriate athletics department procedures for disseminating updates to the list. It is the student-athlete’s responsibility to check with the appropriate or designated athletics staff before using any substance.

The NCAA bans the following drug classes.

  1. Stimulants.
  2. Anabolic agents.
  3. Alcohol and beta blockers (banned for rifle only).
  4. Diuretics and masking agents.
  5. Narcotics.
  6. Cannabinoids.
  7. Peptide hormones, growth factors, related substances and mimetics.
  8. Hormone and metabolic modulators (anti-estrogens).
  9. Beta-2 agonists.

Note:  Any substance chemically/pharmacologically related to all classes listed above and with no current approval by any governmental regulatory health authority for human therapeutic use (e.g., drugs under pre-clinical or clinical development or discontinued, designer drugs, substances approved only for veterinary use) is also banned. The institution and the student-athlete shall be held accountable for all drugs within the banned-drug class regardless of whether they have been specifically identified. Examples of substances under each class can be found at There is no complete list of banned substances.

Substances and Methods Subject to Restrictions:

  • Blood and gene doping.
  • Local anesthetics (permitted under some conditions).
  • Manipulation of urine samples.
  • Beta-2 agonists (permitted only by inhalation with prescription).
  • Tampering of urine samples.

NCAA Nutritional/Dietary Supplements:

Before consuming any nutritional/dietary supplement product, review the product and its label with your athletics department staff. Many nutritional/dietary supplements are contaminated with banned substances not listed on the label.

  • Nutritional/Dietary supplements, including vitamins and minerals, are not well regulated and may cause a positive drug test.
  • Student-athletes have tested positive and lost their eligibility using nutritional/dietary supplements.
  • Many nutritional/dietary supplements are contaminated with banned substances not listed on the label.
  • Any product containing a nutritional/dietary supplement ingredient is taken at your own risk.

Athletics department staff should provide guidance to student-athletes about supplement use, including a directive to have any product checked by qualified staff members before consuming. The NCAA subscribes only to Drug Free Sport AXISTM for authoritative review of label ingredients in medications and nutritional/dietary supplements. Contact Drug Free Sport AXIS at 816-474-7321 or (password ncaa1, ncaa2 or ncaa3).

Some Examples of NCAA Banned Substances in Each Drug Class


Drug Classes Some Examples of Substances in Each Class

Amphetamine (Adderall), Caffeine (Guarana), Cocaine, Dimethylbutylamine (DMBA; AMP), Dimethylhexylamine (DMHA; Octodrine), Ephedrine, Heptaminol, Hordenine, Methamphetamine, Methylhexanamine (DMAA; Forthane), Methylphenidate (Ritalin), Mephedrone (bath salts), Modafinil, Octopamine, Phenethylamines (PEAs), Phentermine Synephrine (bitter orange).

Exceptions: Phenylephrine and Pseudoephedrine are not banned.

Anabolic Agents

Androstenedione, Boldenone, Clenbuterol, DHCMT (Oral Turinabol), DHEA (7-Keto), Drostanolone, Epitrenbolone, Etiocholanolone, Methandienone, Methasterone, Nandrolone, Norandrostenedione, Oxandrolone, SARMS [Ligandrol (LGD-4033); Ostarine; RAD140; S-23], Stanozolol, Stenbolone, Testosterone, Trenbolone.

Alcohol and Beta Blockers (banned for rifle only)

Alcohol, Atenolol, Metoprolol, Nadolol, Pindolol, Propranolol, Timolol.

Diuretics and Masking Agents

Bumetanide, Chlorothiazide, Furosemide, Hydrochlorothiazide, Probenecid, Spironolactone (canrenone), Triameterene, Trichlormethiazide.

Exceptions: Finasteride is not banned.


Buprenorphine, Dextromoramide, Diamorphine (heroin), Fentanyl, and its derivatives, Hydrocodone, Hydromorphone, Methadone, Morphine, Nicomorphine, Oxycodone, Oxymorphone, Pentazocine, Pethidine.


Marijuana, Synthetic cannabinoids (Spice; K2; JWH-018; JWH-073), Tetrahydrocannabinol (THC).

Peptide Hormones, growth factors, related substances and mimetics

Growth hormone (hGH,) Human Chorionic Gonadotropin (hCG), Erythropoietin (EPO), IGF-1 (colostrum; deer antler velvet), Ibutamoren (MK-677).

Exceptions: Insulin, Synthroid and Forteo are not banned.

Hormone and Metabolic Modulators

Aromatase Inhibitors [Anastrozole (Arimidex); ATD (androstatrienedione); Formestane; Letrozole], Clomiphene (Clomid), Fulvestrant GW1516 (Cardarine; Endurobol), SERMS [Raloxifene (Evista); Tamoxifen (Nolvadex)].

Beta-2 Agonists Bambuterol, Formoterol, Higenamine, Norcoclaurine, Salbutamol, Salmeterol.

Any substance that is chemically related to one of the above classes, even if it is not listed as an example, is also banned.

It is your responsibility to check with the appropriate or designated athletics staff before using any substance. Many nutritional/dietary supplements are contaminated with banned substances not listed on the label.

Information about ingredients in medications and nutritional/dietary supplements can be obtained by contacting Drug Free Sport AXIS at 877-202-0769 or (password ncaa1, ncaa2 or ncaa3).